The creature - capable of being the smelliest animal in the world - had evaded capture for six months.
Dozens of calls had been received by the RSPCA but no-one had been able to confine the little terror who has been named Pepe Le Peu after the famous Warner Bros character.
RSPCA Inspector Alison Wilkinson finally blocked Pepe in a stairwell at Joshua Street where he had set up home among rubbish.
And, fortunately, Pepe didn't kick-up a stink, when he was eventually captured.
"It took nearly an hour to 'grasp' him," she said.
"He was hissing and spitting, and did actually spray me but I think his scent glands must have been removed."
Keeping a skunk is legal in the UK and the removal of the anal scent glands, which are used as a defensive weapon, is common amongst those kept as pets.
The RSPCA have not had any reports of a skunk missing so Pepe was likely to have been abandoned.
Pepe is being transported to a skunk specialist in Hemel Hempsted today.


FACTFILE
Skunks use chemicals called thiols to create a potent smell that repels attack from potential predators.
The musk is painful if it gets into the eyes and the smell causes nausea.
Skunks are no bigger than a domestic cat and from the family of mustelids which means mouse-catcher.
The North American version is called mephitis mephitis and has a black and white coat with a busy tail.
They are reared for their fur but can make affectionate pets - with their scent glands removed.
Experts advise tame ones should be fed vegetables, boiled chicken and small amounts of dog food. In the wild, they eat small mammals, insects, foliage - and rummage around in dustbins.